The NEURESCUE device is the first computer-aided aortic occlusion catheter, with intelligent safety feedback and pressure-limited filling. The device is designed with as few user steps as possible, built-in feedback and a high safety profile. These elements are crucial for the time-sensitive situations surrounding the use of aortic balloon occlusion. Several preclinical and clinical investigations have been published, describing procedures that involve aortic occlusion, most of them in time-limited emergency settings [1]. Our future goal is to enable the clinical utility of further intelligent procedures.